Abstract Mouse allergen has long been recognized as an important cause of occupational allergy and asthma, but only recently has it
been implicated in asthma and allergic diseases in community settings. Recent studies have established that mouse allergen
is detectable in most US homes, with strikingly high levels in some inner cities. Inner city homes in major northeastern and
midwestern US urban centers have levels as much as 100-fold higher than those found in other geographic regions. In addition,
about 25% of inner city children with asthma have evidence of IgE sensitization to mouse. Several studies have shown that
the combination of sensitization and exposure to higher levels of mouse allergen is associated with substantial asthma morbidity,
including hospitalization...
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