ACS Meeting News: Sirtris says controversial antiaging compounds act at an allosteric site. (Source: Chemical and Engineering News)
Health Topics » Aging
Category: Aging
In vitro protective effects of Withania somnifera (L.) dunal root extract against hydrogen peroxide and [bgr]-amyloid(1-42)-induced cytotoxicity in differentiated PC12 cells
In this study, an aqueous extract prepared from the dried roots of W. somnifera was assessed for potential protective effects against H2O2- and A[bgr](1-42)-aggregated fibril cytotoxicity by an MTT assay using a differentiated rat pheochromocytoma PC12 cell line. The results suggest that pretreatments of differentiated PC12 cells with aqueous extracts of W. somnifera root significantly protect di
Category: Aging
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Category: Aging
Dietary intake of pterostilbene, a constituent of blueberries, inhibits the {beta}-catenin/p65 downstream signaling pathway and colon carcinogenesis in rats
We reported earlier that pterostilbene (trans-3,5-dimethoxy-4'-hydroxystilbene), a structurally related stilbene found in blueberries, was effective in reducing the incidence and multiplicity of aberrant crypt foci formation in the colon of rats injected with azoxymethane (AOM). Our present study was to identify the chemopreventive potential of pterostilbene with colonic tumor formation as an end
Category: Aging
An Antiinflammatory and Reactive Oxygen Species Suppressive Effects of an Extract of Polygonum Cuspidatum Containing Resveratrol.
Conclusions: The PCE-containing resveratrol has a comprehensive suppressive effect on oxidative and inflammatory stress. PMID: 20534755 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism)
Category: Aging
Update on new therapeutic options for the somatopause.
Authors: Ceda GP, Dall'Aglio E, Morganti S, Denti L, Maggio M, Lauretani F, Andrea A, Ceresini G, Cattabiani C, Valenti G During the last decade, a significant body of evidence has accumulated, indicating that the declining activity of the GH-IGF-I axis with aging might play a role in the development of frailty and in several pathological conditions commonly seen during aging, such as atherosc
Category: Aging
Bradyarrhythmia caused by ginseng in a patient with chronic kidney disease
One of the most popularly used Chinese herbal medicines (CHMs) is ginseng, which is a highly valued herb in the Far East and has gained popularity in the West during the last decades. Ginseng has been reported to have pharmacological effects, including modulation of immune response and anticancer, antiaging, anti-amnestic, cardiovascular protective, and wound-healing effects. It is known that ing
Category: Aging
Is there any scientific evidence supporting antiaging medicine?
The objective of antiaging medicine is to interfere in the normal human biological aging process. Is there any scientific basis to justify classifying antiaging medicine as a medical specialty and not a branch of basic biological science? This review evaluated 110 papers, nine of which (8.2% of the total) reported studies involving human subjects. Only one of these studies was randomized and doub
Category: Aging
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