Content Type Journal ArticleDOI 10.1007/s11882-010-0145-8Authors David P. Skoner, Drexel University College of Medicine, Philadelphia, PA USA Journal Current Allergy and Asthma ReportsOnline ISSN 1534-6315Print ISSN 1529-7322 (Source: Current Allergy and Asthma Reports)
Health Topics
The Hygiene Hypothesis Revisited: Role of Materno-Fetal Interactions
Abstract For 20 years, the hygiene hypothesis has dominated attempts to explain the increasing prevalence of allergic disease. A causal link between maternal innate immune response during pregnancy and disease protection in the offspring was recently demonstrated. Central to this was a systemically diffused signal that downregulated Toll-like receptor expression in placental tissu
Category: Asthma
Effect of acute cold exposure on lung perfusion and tracheal smooth muscle contraction in rabbit
Abstract Acute exposure to cold temperature can affect the respiratory system of those exposed to extreme weather and induces asthma in asthmatic patients. However, the effect on lung perfusion and the pulmonary circulation was not addressed in any previous study. The present study investigates the effects of acute cold exposure on tracheal smooth muscle and lung perfusion. New Zealand
Category: Asthma
Assessment of Pediatric asthma drug use in three European countries; a TEDDY study
Conclusion: This study shows that among all asthma drugs, Ã2-mimetics and inhaled steroids are most often used, also in children without asthma, and with large variability between countries. Linking multi-country databases allows us to study country specific pediatric drug use in a systematic manner without being hampered by methodological differences. This study underlines the potency of health
Category: Asthma
[Review] The role of dendritic and epithelial cells as master regulators of allergic airway inflammation
Lung dendritic cells bridge innate and adaptive immunity, integrating a variety of stimuli from allergens, microbial colonisation, environmental pollution, and innate immune cells into a signal for T lymphocytes of the adaptive immune system. Dendritic cells have a pivotal role in the activation of T helper (Th) 2 cells and allergic inflammation. Lung dendritic cells can also prevent harmful immu
Category: Asthma
Get the basics right first in asthma
âTreatment-resistantâ asthma in children often just needs better managementRelated items from OnMedicaAntibiotic fails to improve lung function in children with CFCharity angry at NICE decision on XolairMore concern over paracetamol link to asthmaPay more heed to parent concern over sick childrenNon-adherence blamed for some âdifficultâ asthma (Source: OnMedica Latest News)
Category: Asthma
Prescription Drug Use Rising in U.S., CDC Reports
Statins, asthma meds, antidepressants and stimulants top the list (Source: The Doctors Lounge - Cardiology)
Category: Asthma
[Review] Role of viral respiratory infections in asthma and asthma exacerbations
Viral respiratory tract infections are common and usually selflimited illnesses. For patients at risk of asthma, or with existing asthma, viral respiratory tract infections can have a profound effect on the expression of disease or loss of control. New evidence has shown that wheezing episodes early in life due to human rhinoviruses are a major risk factor for the later diagnosis of asthma at age
Category: Asthma
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